This test can be performed at any time during your cycle, even if you’re on hormonal treatment. It’s available by our partner clinics.
Endotest is powered by Ziwig’s advanced microRNA (miRNA) technology — a breakthrough in the way we diagnose endometriosis. Unlike traditional diagnosis methods, which often require surgery, Endotest uses a simple saliva sample to detect biological markers linked to the condition.
Endotest doesn’t look for lesions or tissue — it looks for molecular signals.
These signals are based on patterns of microRNA, which are tiny molecules found naturally in your saliva.
Research has shown that people with endometriosis have unique miRNA “signatures” — biological fingerprints that indicate the presence of the condition, even when physical symptoms are unclear or inconsistent.
Sample Preparation: Your saliva is mixed with a solution (lysis buffer) that helps release the genetic material inside your cells.
miRNA Extraction: Using a process called the spin column method, your sample is spun in a centrifuge. This filters out everything except the microRNA, which is isolated and purified.
Analysis: The extracted miRNA is then analysed using next-generation sequencing and artificial intelligence. This identifies whether your microRNA pattern matches those seen in endometriosis patients.
Results: Your results are returned in approx. 4 weeks — giving you clarity without surgery, hospital stays, or long waitlists.
MicroRNA (miRNA) is a type of molecule found in saliva, blood, and other body fluids. It helps regulate how genes are expressed — in other words, how your body functions at a cellular level.
Endotest looks at a combination of over 100 miRNA biomarkers, offering high sensitivity and specificity in detecting endometriosis.
Endotest is CE-marked and backed by clinical studies. In large-scale research, it showed:
Sensitivity of over 97%
Specificity of over 93%
This means the test is highly accurate in identifying those who do (and don’t) have endometriosis — offering results that rival surgical diagnosis, without the invasiveness.
Ziwig Endotest is not suitable if you:
The Ziwig Endotest is a non-invasive saliva test that helps detect signs of endometriosis using microRNA technology. It’s an advanced, accurate alternative to traditional surgical diagnosis.
It’s designed for women aged 18 to 43 experiencing symptoms such as pelvic pain, painful periods, bloating, or infertility. A partner clinic will confirm if it’s right for you.
Yes, the test can still be taken while using hormonal contraceptives.
Not at all. It only requires a saliva sample — no needles, no surgery.
Results are usually available in approx. 4 weeks after your sample reaches the lab.
Endotest has demonstrated sensitivity over 97% and specificity over 93% in clinical studies.
The test is a premium diagnostic tool. Pricing varies slightly by clinic, so we recommend contacting a partner clinic directly for details.
At the moment, the Endotest is not covered by the HSE or standard health insurance plans in Ireland. It is a private diagnostic option.
Speak to your GP or contact one of our partner clinics. They’ll guide you through whether Endotest is appropriate for your symptoms.
Speak with the Endotest.ie Team, or contact a partner clinic to learn if the Endotest is right for you.
📧 Email: endotest@htslabs.ie
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