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ENDOTEST EXPLAINED

Ziwig Endotest

A simple saliva test offering early, non-invasive detection of endometriosis.
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ENDOTEST EXPLAINED

Ziwig Endotest

A simple saliva test offering early, non-invasive detection of endometriosis.
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INNOVATION THAT PUTS YOU FIRSTWhat is Ziwig Endotest?

Ziwig Endotest is a CE-marked in vitro diagnostic test that uses a simple saliva sample to detect endometriosis. It's designed for women aged 18 to 43 who are experiencing symptoms such as:
  • Chronic pelvic pain
  • Painful or heavy periods
  • Pain during sex
  • Painful urination or bowel movements
  • Infertility
  • Shoulder pain during menstruation

This test can be performed at any time during your cycle, even if you’re on hormonal treatment. It’s available by our partner clinics.

Ziwig Endotest
ZIWIG ENDOTEST

How It Works

Advanced science made simple, for your peace of mind.
Ziwig Endotest SalivaSample Endotest.ie

Saliva Collection

You'll provide a saliva sample at your clinic — no needles, no surgery, no discomfort.
Laboratory testing Endotest Endotest.ie

Advanced Analysis

Your sample is analysed using next-generation sequencing and artificial intelligence to detect microRNA patterns associated with endometriosis.
Patient receives her endotest results and learns about next steps

Quick Results

Results are typically available in approx. 3 weeks, offering clarity and a path forward.
Ziwig Endotest SalivaSample Endotest.ie

Saliva Collection

You'll provide a saliva sample at your clinic — no needles, no surgery, no discomfort.
Laboratory testing Endotest Endotest.ie

Advanced Analysis

Your sample is analysed using next-generation sequencing and artificial intelligence to detect microRNA patterns associated with endometriosis.
Patient receives her endotest results and learns about next steps

Quick Results

Results are typically available in approx. 3 weeks, offering clarity and a path forward.
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The Science Behind Endotest

Endotest is powered by Ziwig’s advanced microRNA (miRNA) technology — a breakthrough in the way we diagnose endometriosis. Unlike traditional diagnosis methods, which often require surgery, Endotest uses a simple saliva sample to detect biological markers linked to the condition.

What Makes It Different?

Endotest doesn’t look for lesions or tissue — it looks for molecular signals.
These signals are based on patterns of microRNA, which are tiny molecules found naturally in your saliva.

Research has shown that people with endometriosis have unique miRNA “signatures” — biological fingerprints that indicate the presence of the condition, even when physical symptoms are unclear or inconsistent.

What Happens to My Sample?

After you collect your saliva sample, here’s what happens behind the scenes:
  1. Sample Preparation: Your saliva is mixed with a solution (lysis buffer) that helps release the genetic material inside your cells.

  2. miRNA Extraction: Using a process called the spin column method, your sample is spun in a centrifuge. This filters out everything except the microRNA, which is isolated and purified.

  3. Analysis: The extracted miRNA is then analysed using next-generation sequencing and artificial intelligence. This identifies whether your microRNA pattern matches those seen in endometriosis patients.

  4. Results: Your results are returned in approx. 4 weeks — giving you clarity without surgery, hospital stays, or long waitlists.

Endotest-What-happens-my-sample

What Is microRNA?

MicroRNA (miRNA) is a type of molecule found in saliva, blood, and other body fluids. It helps regulate how genes are expressed — in other words, how your body functions at a cellular level.

Endotest looks at a combination of over 100 miRNA biomarkers, offering high sensitivity and specificity in detecting endometriosis.

Is It Reliable?

Endotest is CE-marked and backed by clinical studies. In large-scale research, it showed:

  • Sensitivity of over 97%

  • Specificity of over 93%

This means the test is highly accurate in identifying those who do (and don’t) have endometriosis — offering results that rival surgical diagnosis, without the invasiveness.

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Why Choose Ziwig Endotest?

  • Highly Accurate: Sensitivity over 97% and specificity over 93%
  • Non-Invasive: No need for surgical procedures like laparoscopy
  • Fast: Receive results in approx. 4 weeks
  • Accessible: Available through partner clinics across Ireland and the UK
Endometriosis Test

Important Considerations

Ziwig Endotest is not suitable if you:

  • Are currently pregnant
  • Have a history of cancer or HIV
  • Have an active infection at the time of testing
  • Have consumed food, used toothpaste, lipstick, tobacco, or chewing gum shortly before the test
Optimistic woman with endotest.ie

CONNECT WITH A CLINIC THAT UNDERSTANDS ENDOMETRIOSISFind a Clinic Near You

We work with a growing network of women’s health clinics and GPs across Ireland.
Search by county or postcode to find your nearest provider.
Optimistic woman with endotest.ie
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Niamh, age 32

“After years of being told everything looked ‘normal’, the Endotest finally validated what I’ve been feeling. I finally feel seen — and supported.”

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Endotest Clinics
RoseClinicBray-Endotest.ie
Unqlife-Endotest.ie
Femina-Endotest.ie
DrUnaConway-Endotest.ie
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FREQUENTLY ASKED QUESTIONS

What You Need to Know Before Taking Endotest

Wondering if Endotest is right for you? Start here.
What is Ziwig Endotest?

The Ziwig Endotest is a non-invasive saliva test that helps detect signs of endometriosis using microRNA technology. It’s an advanced, accurate alternative to traditional surgical diagnosis.

Who can take the test?

It’s designed for women aged 18 to 43 experiencing symptoms such as pelvic pain, painful periods, bloating, or infertility. A partner clinic will confirm if it’s right for you.

Can I take Endotest if I’m on birth control?

Yes, the test can still be taken while using hormonal contraceptives.

Does the test hurt?

Not at all. It only requires a saliva sample — no needles, no surgery.

How long do results take?

Results are usually available in approx. 4 weeks after your sample reaches the lab.

How accurate is the Endotest?

Endotest has demonstrated sensitivity over 97% and specificity over 93% in clinical studies.

How much does the Endotest cost?

The test is a premium diagnostic tool. Pricing varies slightly by clinic, so we recommend contacting a partner clinic directly for details.

At the moment, the Endotest is not covered by the HSE or standard health insurance plans in Ireland. It is a private diagnostic option.

I’m not sure if I need the test?

Speak to your GP or contact one of our partner clinics. They’ll guide you through whether Endotest is appropriate for your symptoms.

Empowered Woman Endotest
TAKE THE FIRST STEP

It's Time to Feel Heard

Speak with the Endotest.ie Team, or contact a partner clinic to learn if the Endotest is right for you.
📧 Email: endotest@htslabs.ie
📍 Find a Clinic 




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